Sigma 阿霉素 盐酸盐

Sigma 阿霉素 盐酸盐

产品编号 D1515 | CAS号 25316-40-9 | SIGMA

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包装:10 mg in glass bottle Biochem/physiol Actions

Naturally fluorescent anthracycline antibiotic, anticancer drug. Doxorubicin is a substrate of MRP1 which was first cloned from a DOX-resistant lung cancer cell line. Fluorescent property has been exploited for the measurement of drug efflux pump activities as well as resolving the important question of intracellular localization of various multidrug resistance proteins and the role of subcellular organelles (Golgi and lysosome) in the sequestration of drugs and its implication in drug resistant phenotypes.


Adriamycin 为以下机构的注册商标: RDF Pharmacia & Upjohn S.P.A.

Protocols & Applications

Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

Related Categories Antibiotics, Antibiotics A to Z, Antibiotics A-F, Antibiotics by Application, Antineoplastic and Immunosuppressive Antibiotics,

assay 98.0-102.0% (HPLC)
mp 216 °C (dec.)(lit.)
solubility H2O: soluble50 mg/mL, clear
Mode of action DNA synthesis | interferes
antibiotic activity spectrum viruses
storage temp. 2-8°C